1- FND_Diagnostics
Setting this profile option to YES, will add anew link "Diagnostics" at top right on page, that allow developer to trace logs. To add log when coding use the following code in Controller or Application Module

In Controller write this code:-
pageContext.writeDiagnostics(this, "Phrase will be added to logs", 1);
In Application Module write this code
getOADBTransaction().writeDiagnostics(this, "Phrase will be added to logs", 1);

2- Personalize Self-Service Defn
 Set this profile to Yes to allow personalization. 

3- FND: Personalization Region Link Enabled :
Set this profile to  Yes  show "Personalize  Region" links above each  region in a page.

4- Disable Self-Service Personalization
Yes will disable all personalization at any level.

5- FND: Personalization Document Root Path
Set this profile option to a directory at application server machine which will contain import/export personalization files.